It’s said that dogs are man’s best friends. In this case, canada goose uk outlet dogs at the University of Pennsylvania School of Veterinary Medicine’s Working Dog Center may become women’s best friends.
A new study hopes to put dogs’ keen noses to use detecting ovarian cancer, a type of cancer with a poor prognosis because it tends to be discovered late.
Dr. Jody Piltz Seymour, a Narberth resident who lost both an aunt and her mother in law to ovarian cancer, is the driving force behind the study that harnesses researchers at the veterinary center, Penn’s physics department, Penn Medicine’s division of gynecologic oncology and the Monell Chemical Senses Center. An $80,000 grant from Kaleidoscope of Hope Ovarian Cancer Foundation will fund the study.
”It’s so exciting,” canada goose uk shop said Piltz Seymour. ”It’s really very, very exciting. Ovarian canada goose jacket outlet cancer has a poor prognosis because it’s caught too late. But it has an excellent prognosis if it’s caught early. That’s why this work is so important. If we can find a screening test to canada goose factory sale find it early we can change the canada goose coats whole prognosis.”
As for her relations, Piltz Seymour said, ”What was so shocking is canada goose outlet new york city both their cancers were detected very, very late.” Another aunt died from pancreatic cancer. ”There’s no clinical screening test for both these cancers. No effective screening tool for ovarian cancer exists and canada goose outlet online the symptoms of ovarian cancer mimic other problems. canada goose outlet These include bloating, weight gain, constipation and more frequent urination.
More than 60 percent of patients are diagnosed after the disease canada goose black friday sale has spread to their lymph nodes or other sites in the body. Doctors currently use their senses of sight, sound and touch when diagnosing ovarian cancer.
Piltz Seymour, who is an ophthalmologist, said she’d read about studies in scientific literature that showed that dogs had been able to recognize and signal that different types of cancer were present in blood and urine samples.
”Nobody took it to the next step,” she said. Scientists would find that dogs had this ability and ”just move on. We want to move it forward to use it in a clinically applicable way.”
She had the idea to ”bring together a team of highly skilled, highly respected researchers,” she said. Scientists already know that volatile organic compounds or odorants are altered in the earliest stages of ovarian cancer, before the cancer can be detected by current methods. Detection dogs and electronic devices can detect tiny quantities of those odorants. Tissue and blood samples from healthy patients and patients who have ovarian cancer will be collected by Penn Medicines division of gynecologic oncology. These will be shared with the Working Dog Center to train the dogs. He said doctors often used their sense of smell to detect diseases in the past. ”In this research, we are reaching back to move forward by using sensitive canada goose outlet uk biological and analytical sensors to detect ovarian cancer’s odorous signature,” said Preti, an adjunct professor in Penn Medicine’s department of dermatology. from the department of physics at Penn will use nanotechnology sensors to replicate what the dogs are sensing, which will make the ovarian cancer test that the researchers hope to discover more widely canada goose clearance sale available, said Piltz Seymour.
”Our preliminary work is going to be done on blood samples,” said Piltz Seymour. ”We’re not going to bring a dog into the examination room.”
”So many people have shared their anecdotal stories that dogs have detected their cancers,” she said.
In this pilot study, the Working Dog Center will train three dogs to detect cancer. The dogs, which are fostered in private homes, begin working at four months, said Piltz Seymour. Other dogs at the canada goose outlet in usa Working Dog Center learn how to detect bombs and drugs or are involved in search and https://www.dvu-nds.de rescue.
Piltz Seymour, a glaucoma specialist, has been a clinical researcher and on faculty at Penn for 14 years. An ophthalmologist for 23, years Piltz Seymour is canada goose outlet parka also in private practice with offices in Ardmore and Bucks County.
She’s married and the mother of two daughters ages 19 canada goose outlet canada and 16.
”I wanted to use my expertise in clinical research to move this forward,” she said. ”I put the team together and we all worked together on the grant funding. My job is to keep everything coordinated.”
Piltz Seymour noted that ovarian cancer is associated with the BRCA mutation, a genetic mutation that also increases the risk of breast cancer.
”In the future we plan a separate official canada goose outlet study with the BRCA mutation,” she said.
”I’m just very excited about working with canada goose outlet reviews this wonderful group of researchers to find a screening test that can greatly impact the prognosis for women who have this serious cancer,” said Piltz Seymour. ”We hope this Canada Goose sale is a first step in a long research program.”
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